Hong Bu, born in 1984 in Urumqi, Xinjiang Autonomous Region, China, began playing the violin at age 4 and was accepted in the Music School of the Central Conservatory of Music in Beijing in 1997, where she started playing viola under the direction of Wang Shaowu.
Entering the Central Conservatory of Music in 2003, Hong majored in orchestra, studying under Wing Ho. She won 1st prize in the 2004 Instrumental Music Competition, Beijing National Music Festival. She joined the China Youth Symphony Orchestra that year, participating with the orchestra in the Beethoven fest in Bonn, Germany and in the Pacific Music Festival in Japan.
In 2005 she joined the Seiji Ozawa Ongaku-Juku Orchestra at the invitation of Maestro Seiji Ozawa. As a recipient of the Robert H. N. Ho Family Foundation Orchestral Fellowship in 2007, Hong studied and played in the Hong Kong Philharmonic Orchestra, and in 2008 became a formal member of the orchestra.
In 2010, Hong Bu started working in the orchestra of National Center for the Performing Arts, Beijing while being admitted to the Master degree program at Indiana University Bloomington (IUB) Jacobs School of music, U.S., where her main teacher was Prof. Arad Atar. While at the IUB, she became a principal viola with the University´s Philharmonic orchestra.
After graduation from IUB in 2012, Hong was selected to attend Keshet Eilon string master course in Israel.
In September 2013, Hong Bu was hired by Capital Normal University as a chamber music tutor and viola teacher.